Thermo Fisher Scientific MTHFD2 Polyclonal Antibody
Thermo Fisher Scientific MTHFD2 폴리클로날 항체는 인간 MTHFD2 단백질을 인식하며 WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 높은 종간 반응성과 안정적인 보관 특성을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 2 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| Immunoprecipitation (IP) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 30–304 of Human MTHFD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.13 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545645 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, SK-N-DZ, SK-N-SH
- Predicted reactivity: Mouse (95%), Rat (93%), Zebrafish (86%), Xenopus laevis (90%), Chicken (92%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and requires magnesium and inorganic phosphate for activity. Formation of the enzyme-magnesium complex allows NAD binding. Alternative splicing results in two transcripts, one protein-coding and one non-coding. A pseudogene is located on chromosome 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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