Thermo Fisher Scientific Rat GLUT4 (aa 493-509) Synthetic Peptide

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

-

Product Specifications

Species Reactivity

Rat

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

purified

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

PEP-283 is a 19 amino acid synthetic peptide whose sequence is derived from rat GLUT4 protein. The sequence of this peptide is (amino to carboxy terminus): E (493)-Q-E-V-K-P-S-T-E-L-E-Y-L-G-P-D-E - N-D (509)

This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, GLUT4, catalog # PA1-1065. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.

Reconstitute with 0.1 mL of distilled water.

Target Information

This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.