Thermo Fisher Scientific COPA Polyclonal Antibody
Thermo Fisher Scientific의 COPA Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 토끼 유래 다클론 항체입니다. Western blot 및 면역침전(IP)에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 단백질 수송 연구에 적합합니다.
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Applications
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1174 to 1224 of human Coatomer Protein Complex, Subunit Alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, representing subunits of a complex known as coatomer.
The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP.
The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. The N-terminal 25 amino acids of alpha-COP encode the bioactive peptide xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.
Alternative splicing results in multiple splice forms encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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