Thermo Fisher Scientific MADCAM1 Monoclonal Antibody (OTI1E1), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:4,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The MADCAM1 protein is an endothelial cell adhesion molecule that interacts preferentially with leukocyte beta7 integrin LPAM-1 (α4β7), L-selectin, and VLA-4 (α4β1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues.
It belongs to the immunoglobulin family and is similar to ICAM1 and VCAM1.
At least seven alternatively spliced transcripts encoding different protein isoforms have been identified, though not all full-length variants are characterized.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.