Thermo Fisher Scientific EHMT1/GLP1 Polyclonal Antibody, Biotin
EHMT1/GLP1 단백질을 인식하는 Biotin 결합 토끼 폴리클로날 항체입니다. Western blot, ELISA, IP 등에 사용 가능하며, 인간 및 생쥐 시료에 반응합니다. 고순도 친화 크로마토그래피 정제, 안정한 액상 형태로 -20°C 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 950–100 of human Histone-lysine N-methyltransferase EHMT1 / GLP1 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
EHMT1 (also known as EUHMTASE1) is a histone methyltransferase that methylates Lys-9 of histone H3 in vitro. H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is likely targeted to histone H3 by DNA-binding proteins such as E2F6, MGA, MAX, and/or DP1. During the G0 phase, it may contribute to silencing MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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