Thermo Fisher Scientific p11 (Calpactin I Light Chain/Annexin II) Polyclonal Antibody
S100A10(Annexin II light chain)을 인식하는 Thermo Fisher Scientific의 닭 유래 다클론 항체. IHC에 사용 가능하며, 1:100–1:600 희석 권장. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관. 연구용 전용.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:600
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CNQKDPLAVDK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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