Thermo Fisher Scientific RANBP10 Polyclonal Antibody
RANBP10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC에 사용 가능하며, 인간 및 생쥐 시료에 반응. 항원 친화 크로마토그래피로 정제된 고품질 항체로 연구용으로 적합.
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Thermo Fisher Scientific RANBP10 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1–2 µg/mL
- Immunohistochemistry (IHC): 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the center of human RANBP10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C up to 3 months; for long-term storage, store at −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153726 |
Product Specific Information
- Suggested positive control: Human skeletal muscle tissue lysate
- This antibody (PA5-20930) can be used with blocking peptide PEP-1044
Target Information
RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor with high sequence similarity to RANBP9. It is expressed in the cytoplasm of mature megakaryocytes and platelets, localizing to polymerized noncentrosomal microtubules. RANBP10 exhibits guanine nucleotide exchange factor activity toward RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation, and nuclear envelope assembly. Depletion of RANBP10 disrupts microtubule filaments, indicating its critical role in maintaining microtubule dynamics.
Usage Note
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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