Thermo Fisher Scientific Locusta migratoria c-Met Polyclonal Antibody
Locusta migratoria c-Met 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 높은 특이성과 안정성을 제공. 단백질 G로 정제된 액상 형태로 연구용에 적합.
- 판매단위
- pk
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Thermo Fisher Scientific Locusta migratoria c-Met Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Insect |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Locusta migratoria Met protein (1–329aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.138 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2902167 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies. After activation by its ligand, MET interacts with PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. These interactions lead to activation of signaling cascades including RAS-ERK, PI3K-AKT, and PLCγ-PKC pathways.
MET plays a role in embryonic development including gastrulation, muscle and neuron development, angiogenesis, and kidney formation. In adults, it is involved in wound healing, organ regeneration, and tissue remodeling.
MET has been associated with various cancers such as gastric, renal, and breast, making it a target for cancer therapeutics and diagnostic research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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