Thermo Fisher Scientific GPS2 Polyclonal Antibody
GPS2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 사용 가능. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. 인간, 마우스, 랫트 반응성. -20°C 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: [References not provided]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GPS2 (Accession Q13227), corresponding to amino acid residues R20–L70 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851027 |
Product Specific Information
Antibody detects endogenous levels of total GPS2.
Target Information
This gene encodes a protein involved in G protein–mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene can suppress RAS- and MAPK-mediated signaling and interfere with JNK activity, suggesting a role in signal repression.
The encoded protein is an integral subunit of the NCOR1–HDAC3 complex, which inhibits JNK activation through this subunit and may provide an alternative mechanism for hormone-mediated antagonism of AP1 function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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