Thermo Fisher Scientific SALF Polyclonal Antibody
Thermo Fisher Scientific의 SALF Polyclonal Antibody는 인간 STON1 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot과 면역세포화학(ICC/IF)에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human STON1 (Accession Q9Y6Q2), corresponding to amino acid residues P698–Q735 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818235 |
Product Specific Information
Antibody detects endogenous levels of total STON1.
Target Information
Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of:
- N-terminal proline-rich domain
- Central region of homology specific to human stoned B-like proteins
- C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes
Co-transcription of this gene and the neighboring downstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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