Thermo Fisher Scientific SEMA6D Polyclonal Antibody
Human SEMA6D 단백질의 N-말단 펩타이드(aa 21–70)에 특이적인 Rabbit Polyclonal Antibody. Western blot에 0.2–1 µg/mL로 사용 가능. 액상 형태로 0.5 mg/mL 농도, PBS + 2% sucrose buffer에 보관. -20°C에서 보관하며 반복 동결/해동을 피함.
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Applications
Western Blot (WB)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human SEMA6D (aa 21–70) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606530 |
Product Specific Information
Peptide sequence:
VSFPEDDEPL NTVDYHYSRQ YPVFRGRPSG NESQHRLDFQ LMLKIRDTLY
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 100%
Target Information
Semaphorins are a large family of secreted and membrane-associated proteins involved in axon guidance, fasciculation, branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain in the N-terminal extracellular region. Additional motifs in the C-terminal region classify them into distinct subfamilies.
Transmembrane semaphorins, including SEMA6D, act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that undergoes alternative splicing, producing six transcript variants. Expression of these isoforms is regulated in a tissue- and development-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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