Thermo Fisher Scientific JTB Polyclonal Antibody
JTB 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ELISA, IP에 사용 가능. 인체, 마우스, 랫트 반응성. 합성 펩타이드 면역원 기반, 액상 형태로 -20°C 보관. 세포 증식 및 유사분열 연구용.
- 카탈로그번호
- JTB-101AP
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 100–146 of human Jumping Translocation Breakpoint (JTB) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), which regulates mitosis and ensures correct chromosome alignment and segregation. The CPC is also required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity and inhibits apoptosis induced by TGFB1. Overexpression leads to mitochondrial swelling and reduced membrane potential.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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