Thermo Fisher Scientific TIM-4 Monoclonal Antibody (2C6A3)
인간 TIM-4 단백질을 인식하는 마우스 단클론 항체로 다양한 면역학적 분석(WB, ICC/IF, Flow, ELISA)에 사용 가능. 고순도 Protein G 정제, 액상 형태, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications 및 Tested Dilution
| 응용 분야 | 희석 배수 |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C6A3 |
| Immunogen | Purified recombinant fragment of human TIMD4 (AA: extra 25–314) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090730 |
Target Information
The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors involved in the regulation of T helper (Th)-1 and -2 cell-mediated immunity. TIM-4, preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, leading to T-cell expansion and cytokine production. Unlike other TIM family members, TIM-4 lacks a tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and may be considered as a candidate disease/predisposition gene for asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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