Thermo Fisher Scientific SF3A2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SF3A2 protein. Validated for WB, IHC(P), and ICC/IF applications. High purity via antigen affinity chromatography. Supplied in PBS with glycerol and sodium azide for stability. Suitable for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SF3A2. Recombinant protein control fragment (Product #RP-98921). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647176 |
Product Specific Information
Immunogen sequence:
SSSESNRDRR ERLRQLALET IDINKDPYFM KNHLGSYECK LCLTLHNNEG SYLAHTQGKK HQTNLARRAA KEAKEAPAQP APEKVKVE
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2, and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing.
Subunit 2 interacts with subunit 1 through its amino-terminus, while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP.
Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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