Thermo Fisher Scientific AMSH Polyclonal Antibody
AMSH 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제 및 고순도 액상 형태로 제공되며, 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human AMSH (amino acids 331–420) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokine-mediated signal transduction in the JAK-STAT cascade requires adaptor molecules. One such adaptor contains an SH3 domain essential for MYC induction and cell growth. The AMSH protein binds to the SH3 domain of this adaptor, playing a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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