Thermo Fisher Scientific SNX15 Polyclonal Antibody
SNX15 단백질을 인식하는 염소 폴리클로날 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 0.5 mg/mL 농도의 액상 형태입니다. TBS 버퍼(pH 7.3, 0.5% BSA)로 보관하며, -20°C에서 냉동 보관이 권장됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EEILRLHLSQLPP) corresponding to the C-terminus amino acids of SNX15 (aa 330–342) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982940 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
The SNX15 gene encodes a member of the sorting nexin family, which contains a phox domain involved in phosphoinositide binding and intracellular trafficking. Overexpression of SNX15 decreases the processing of insulin and hepatocyte growth factor receptors due to mislocalization of furin, the endoprotease responsible for receptor cleavage. This protein plays a role in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants, and read-through transcription also exists with the upstream ADP-ribosylation factor-like 2 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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