Thermo Fisher Scientific KCNK2 Polyclonal Antibody
KCNK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 IHC(P) 응용에 적합하며, 인간, 마우스, 랫트 시료 반응. 1 mg/mL 농도의 액상형 비결합 항체로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: [References not provided]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KCNK2 (Accession O95069), corresponding to amino acid residues S4–I54 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900088 |
Product Specific Information
Antibody detects endogenous levels of total KCNK2.
Target Information
TREK-1 (KCNK2) is a two-pore-domain background potassium channel expressed throughout the central nervous system.
It is activated by polyunsaturated fatty acids, lysophospholipids, and volatile anesthetics, and regulated by various neurotransmitters.
Alterations in TREK-1 function or regulation may influence mood and anesthetic response, making it a potential target for new therapeutic agents in anesthesiology and neurology, such as antidepressants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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