Thermo Fisher Scientific BNIP2 Polyclonal Antibody
BNIP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적 액상 형태로 연구용에 최적화.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human BNIP2, amino acids 115–220 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
BNIP-2 (also known as Nip2 or Nip21) shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). By binding to Cdc42GAP, BNIP-2 enhances its GTPase activity, promoting GTP hydrolysis of Cdc42 and mediating signaling pathways involving receptor kinases, small GTPases, and apoptotic proteins.
Nix (Nip3L or Bnip3L) is closely related to BNIP-3, and both localize to mitochondria where they interact with Bcl-2 proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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