Thermo Fisher Scientific AMACR Monoclonal Antibody (UMAB68), UltraMAB
AMACR 단백질을 표적으로 하는 UMAB68 클론의 마우스 단일클론 항체로, IHC 및 ICC/IF 실험에 적합합니다. 인간 시료 반응성이 있으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능하며, 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB68 |
| Immunogen | Full length human recombinant protein of human AMACR produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme in the β-oxidation of branched-chain fatty acids.
High expression of P504S protein is observed in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-embedded samples.
Expression is also detected in premalignant lesions such as high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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