Thermo Fisher Scientific FGD5 Polyclonal Antibody
Thermo Fisher Scientific의 FGD5 Polyclonal Antibody는 인간 FGD5 단백질을 인식하는 토끼 유래 IgG 항체입니다. IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. VEGF-유도 CDC42 활성화 연구 등 혈관 내피세포 연구에 적합합니다.
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- PA553948
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- pk
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FGD5 (amino acids 910–1049) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641604 |
Product Specific Information
Immunogen sequence:
MLQHLNLDFH GAVMRALDDM DHEGRDTLAR EELRQGLSEL PAIHDLHQGI LEELEERLSN WESQQKVADV FLAREQGFDH HATHILQFDR YLGLLSENCL HSPRLAAAVR EFEQSVQGGS QTAKHRLLRV VQRLFQYQVL
Highest antigen sequence identity to the following orthologs:
- Mouse: 74%
- Rat: 76%
Target Information
FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation and may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement, and proliferation. It may also play a role in regulating the actin cytoskeleton and cell shape.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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