Thermo Fisher Scientific muscarinic Acetylcholine Receptor 1 Polyclonal Antibody
Western blot, IHC, ELISA에 적합한 muscarinic Acetylcholine Receptor 1 항체. Rabbit polyclonal IgG로 Goat, Human, Mouse, Rat 반응성. KLH 결합 합성 펩타이드(aa 321-420)로 면역화. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적 액상 형태.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Goat, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human muscarinic Acetylcholine Receptor 1 (amino acids 321–420) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. Their functional diversity is defined by acetylcholine binding, leading to cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence acetylcholine effects in the central and peripheral nervous system.
Muscarinic cholinergic receptor 1 mediates vagally-induced bronchoconstriction and regulates acid secretion in the gastrointestinal tract. The gene encoding this receptor is localized to chromosome 11q13.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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