Thermo Fisher Scientific Phospho-LKB1 (Ser334) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human LKB1 (Phospho-Ser334) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LKB1,uniProtId:Q15831-1,ncbiNodeId:9606,antigenRange:318-345,antigenLength:433,antigenImageFileName:PA5-64592_LKB1_Q15831-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64592_LKB1_Q15831-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2663373

Product Specific Information

Phospho-LKB1 (Ser334) Polyclonal Antibody detects endogenous levels of LKB1 only when phosphorylated at Ser334.

Target Information

LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.