Thermo Fisher Scientific RBBP6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RBBP6. Recombinant protein control fragment (Product #RP-102914). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RBBP6,uniProtId:Q7Z6E9-1,ncbiNodeId:9606,antigenRange:1546-1640,antigenLength:1792,antigenImageFileName:PA5-59697_RBBP6_Q7Z6E9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59697_RBBP6_Q7Z6E9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646354

Product Specific Information

Immunogen sequence: KATYDTKRPN EETKSVDKNP CKDREKHVLE ARNNKESSGN KLLYILNPPE TQVEKEQITG QIDKSTVKPK PQLSHSSRLS SDLTRETDEA AFEPD

Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 75%.

Target Information

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.