Thermo Fisher Scientific TTC5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TTC5. Recombinant protein control fragment (Product #RP-100595). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TTC5,uniProtId:Q8N0Z6-1,ncbiNodeId:9606,antigenRange:128-226,antigenLength:440,antigenImageFileName:PA5-60894_TTC5_Q8N0Z6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-60894_TTC5_Q8N0Z6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649080

Product Specific Information

Immunogen sequence: GALTHCRNKV SLQNLSMVLR QLRTDTEDEH SHHVMDSVRQ AKLAVQMDVH DGRSWYILGN SYLSLYFSTG QNPKISQQAL SAYAQAEKVD RKASSNPDL

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Target Information

Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.