Thermo Fisher Scientific GluR4 Polyclonal Antibody
Thermo Fisher Scientific의 GluR4 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 Rabbit IgG 항체입니다. Western blot과 ELISA에 사용 가능하며, 신경전달 관련 Glutamate receptor 연구에 적합합니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:4,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 254–433 of human GluR4/GluA4/GRIA4 (NP_0010707121) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.92 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901234 |
Product Specific Information
Positive Samples: SH-SY5Y, B cells, Mouse brain, Mouse liver, Mouse kidney, Mouse spinal cord, Rat brain
Immunogen Sequence:
HGGANVTGFQ LVDFNTPMVI KLMDRWKKLD QREYPGSETP PKYTSALTYD GVLVMAETFR SLRRQKIDIS RRGNAGDCLA NPAAPWGQGI DMERTLKQVR IQGLTGNVQF DHYGRRVNYT MDVFELKSTG PRKVGYWNDM DKLVLIQDVP TLGNDTAAIE NRTVVVTTIM PLMKNPILRN
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. These receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas NMDA receptors are characterized by slow kinetics and high Ca²⁺ permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-116603_GluR4_P48058-1_Rabbit.svg, PA5-116603_GluR4_P48058-1_Rabbit_PDP.jpeg)
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