Thermo Fisher Scientific GluR4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:4,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

Positive Samples: SH-SY5Y, B cells, Mouse brain, Mouse liver, Mouse kidney, Mouse spinal cord, Rat brain

Immunogen Sequence:
HGGANVTGFQ LVDFNTPMVI KLMDRWKKLD QREYPGSETP PKYTSALTYD GVLVMAETFR SLRRQKIDIS RRGNAGDCLA NPAAPWGQGI DMERTLKQVR IQGLTGNVQF DHYGRRVNYT MDVFELKSTG PRKVGYWNDM DKLVLIQDVP TLGNDTAAIE NRTVVVTTIM PLMKNPILRN

Target Information

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. These receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas NMDA receptors are characterized by slow kinetics and high Ca²⁺ permeability.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: PA5-116603_GluR4_P48058-1_Rabbit.svg, PA5-116603_GluR4_P48058-1_Rabbit_PDP.jpeg)