Thermo Fisher Scientific ABH1 Recombinant Rabbit Monoclonal Antibody (JE54-26)
ABH1 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot 및 IHC(파라핀) 분석에 적합합니다. 높은 특이성과 재현성을 제공하며, Protein A로 정제된 액상 형태로 공급됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE54-26 |
| Immunogen | Synthetic peptide within C-terminal Human ALKBH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931352 |
Target Information
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism for DNA alkylation damage repair. It reverses damage through oxidative demethylation of 1-methyladenine and 3-methylcytosine.
Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate, and iron.
May play a role in placental trophoblast lineage differentiation. Exhibits DNA lyase activity and introduces double-stranded breaks at abasic sites, cleaving both single-stranded and double-stranded DNA, with greatest activity toward double-stranded DNA with two abasic sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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