Thermo Fisher Scientific PKC theta Polyclonal Antibody
PKC theta 단백질을 인식하는 Rabbit Polyclonal 항체. 인체 유래 단백질에 반응하며, ICC/IF 분석에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PKC theta. Recombinant protein control fragment (Product # RP-107907) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2857117 |
Product Specific Information
Immunogen sequence:
LEKEAKDLLV KLFVREPEKR LGVRGDIRQH PLFREINWEE LERKEIDPPF
Target Information
Protein Kinase C (PKC) isoforms are serine/threonine kinases involved in signal transduction pathways that govern a wide range of physiological processes including differentiation, proliferation, gene expression, brain function, membrane transport, and the organization of cytoskeletal and extracellular matrix proteins.
PKC acts as a key regulator of cell cycle transitions, including cell cycle entry and exit, as well as G1 and G2 checkpoints.
There are at least 12 PKC isoforms identified in humans: alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu.
These isoforms differ in structure, localization, tissue distribution, and response to extracellular signals.
PKC beta II is expressed in cardiac muscle, intestinal epithelium, kidney, and pancreas, and is associated with cell cycle progression and cancer proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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