Thermo Fisher Scientific PSMD10 Polyclonal Antibody
Thermo Fisher Scientific의 PSMD10 폴리클로날 항체는 인간, 생쥐, 랫트에 반응하며 Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSMD10. Recombinant protein control fragment (Product #RP-92176). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646067 |
Product Specific Information
Immunogen sequence:
EGCVSNLMVC NLAYSGKLEE LKESILADKS LATRTDQDSR TALHWACSAG HTEIVEFLLQ LGVPVNDKDD AGWSPLHIAA SAGRDEIVKA LLGKGAQVNA VNQNGCTPL
Sequence identity:
- Mouse: 94%
- Rat: 85%
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
- 20S core: 4 rings of 28 subunits (2 rings of 7 alpha, 2 rings of 7 beta subunits)
- 19S regulator: base (6 ATPase + 2 non-ATPase subunits) and lid (up to 10 non-ATPase subunits)
Proteasomes are widely distributed in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome is essential for MHC class I peptide processing.
This gene encodes a non-ATPase subunit of the 19S regulator. Two isoforms are described, and pseudogenes are identified on chromosomes 3 and 20.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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