Thermo Fisher Scientific FIG4/SAC3 Polyclonal Antibody
FIG4/SAC3 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Protein A로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human FIG4 (amino acids 1–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene belongs to the SAC domain-containing protein family. The SAC domain, approximately 400 amino acids long with seven conserved motifs, exhibits phosphoinositide phosphatase activity. The yeast homolog, Sac1p, regulates various phosphoinositides and influences cellular processes such as actin cytoskeleton organization, Golgi function, and vacuole morphology maintenance. Membrane-bound phosphoinositides act as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 4J.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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