Thermo Scientific™

Sulfo-EMCS (N-ε-maleimidocaproyl-oxysulfosuccinimide ester)

Thermo Scientific Pierce Sulfo-EMCS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of자세히 알아보기

Thermo Scientific Pierce Sulfo-EMCS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length spacer arm (9.4 angstroms).

Features of Sulfo-EMCS:

• Reactive groups: sulfo-NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Sulfo-NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming stable thioether linkages
• Non-cleavable
• Water-soluble (compare to EMCS)
• Aliphatic spacer offers low potential for eliciting an immune response

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
EMCS (N-ε-malemidocaproyl-oxysuccinimide ester)

사양

화학물질 반응성Amine-Sulfhydryl

CleavableNo

설명Sulfo-EMCS

분자량410.33

페길레이티드No

스페이서 암 길이9.4 Å

세포 투과성No

배송 조건Ambient

제품라인Pierce™

라벨링 방법Chemical Labeling

교차결합제 유형Heterobifunctional

반응성 부분Maleimide, Sulfo-NHS Ester

스페이서Short (<10 Å)

형태Powder

수량50 mg

용해도Water

형식Standard

수용성Yes

제품 유형Crosslinker

Unit SizeEach