Thermo Fisher Scientific BEX1/BEX2 Polyclonal Antibody
BEX1/BEX2 단백질을 인식하는 Rabbit Polyclonal 항체. WB 및 IHC에 사용 가능. 합성 펩타이드를 면역원으로 제작. 종양 억제 및 세포사멸 관련 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 2–40 of mouse BEX1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2243487 |
Product Specific Information
- Reconstitute with 100 µL of distilled water.
- The peptide is homologous in rat.
Target Information
BEX1/BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription.
BEX1/BEX2 has been identified as a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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