Thermo Fisher Scientific GPD1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human GPD1, validated for WB, IHC, and ICC. Detects GPD1 involved in carbohydrate and lipid metabolism. Recommended positive controls: HepG2, mouse brain. Suitable for multiple species with high predicted reactivity.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 37–296 of Human GPD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545447 |
Product Specific Information
- Recommended positive controls: HepG2, mouse brain
- Predicted reactivity: Mouse (96%), Rat (95%), Xenopus laevis (84%), Pig (94%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD⁺. The cytosolic and mitochondrial forms of glycerol-3-phosphate dehydrogenase form a glycerol phosphate shuttle that transfers reducing equivalents from the cytosol to mitochondria. Mutations in this gene can cause transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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