Thermo Fisher Scientific Phospho-c-Jun (Tyr170) Polyclonal Antibody
인간, 생쥐, 랫트에서 반응하는 Rabbit Polyclonal 항체로 Tyr170 위치의 인산화된 c-Jun을 검출. Western blot에 적합하며 Protein A로 정제된 액상 형태. 안정한 저장용 PBS 버퍼와 50% 글리세롤 포함, -20°C 보관 권장.
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Thermo Fisher Scientific Phospho-c-Jun (Tyr170) Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence that includes phosphorylation site of tyrosine 170 (P-V-Y(p)-A-N) derived from human c-Jun and conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | Dulbecco’s PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. It is involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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