Thermo Fisher Scientific CYFIP1 Polyclonal Antibody
CYFIP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합. 인간, 생쥐, 랫드 반응성. 고순도 항원 친화 크로마토그래피 정제 및 액상 형태로 제공.
- 카탈로그번호
- PA531984
- 판매단위
- pk
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Thermo Fisher Scientific CYFIP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–309 of Human CYFIP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549457 |
Product Specific Information
- Recommended positive controls: HeLa, mouse brain, rat brain
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (93%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CYFIP1 is a component of the CYFIP1–EIF4E–FMR1 complex that binds to the mRNA cap and mediates translational repression. In this complex, CYFIP1 acts as an adapter between EIF4E and FMR1, promoting FMR1’s translation repression activity in the brain. It is involved in membrane ruffle and lamellipodia formation, axon outgrowth, and epithelial morphogenesis, and may function as an invasion suppressor in cancers. CYFIP1 binds to F-actin but not RNA.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-31984_CYFIP1_Q7L576-1_Rabbit_PDP.jpeg)
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