Thermo Fisher Scientific CCDC123 Polyclonal Antibody
Human CCDC123 단백질을 인식하는 Rabbit Polyclonal Antibody. ICC/IF에 사용 가능하며 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 0.3 mg/mL 농도로 제공. CEP123 단백질 연구 및 섬모 형성과정 연구에 적합.
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Applications and Tested Dilution
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CCDC123. Recombinant protein control fragment (Product # RP-98218) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639373 |
Product Specific Information
Immunogen sequence:
KINRKSQKKI EVLKKQVEKA MGNEMSAHQY LANLVGLAEN ITQERDSLMC LAKCLESEKD GVLNKVIKSN IRLGKLEEKV KGYKKQAALK LGDISHRLLE QQEDFAGKTA QYRQEM
Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 78%
Target Information
CCDC123 (also known as CEP123 or CEP89) is involved in primary ciliogenesis and mitochondrial metabolism, potentially modulating complex IV activity. It localizes to the distal appendages of the mother centriole, with localization being cell cycle-dependent. CEP123 depletion can cause defects in ciliary vesicle formation and inhibit ciliary vesicle formation at the distal end of the mother centriole. It may play a role in regulating membrane recruitment to the centrosome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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