Thermo Fisher Scientific HnRNP Q Polyclonal Antibody
HnRNP Q 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC(P), ICC/IF에 적합하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. PBS buffer(50% glycerol) 내 보관하며, -20°C에서 안정적으로 저장 가능합니다.
- 카탈로그번호
- PA5118818
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SYNCRIP (Accession O60506), corresponding to amino acid residues G248–T298 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903318 |
Product Specific Information
Antibody detects endogenous levels of total hnRNP Q.
Target Information
Heterogeneous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoforms 1, 2, and 3 associate with pre-mRNA, splicing intermediates, and mature mRNA-protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences and is part of the APOB mRNA editosome complex, possibly modulating posttranscriptional C-to-U RNA-editing of APOB mRNA by binding to A1CF, APOBEC1, or RNA itself. Involved in translationally coupled mRNA turnover and cytoplasmic mRNA decay. Isoform 3 may participate in vesicle-based mRNA transport via interaction with synaptotagmins. Also a component of the GAIT complex, mediating interferon-gamma-induced, transcript-selective translation inhibition during inflammation by binding to GAIT elements in 3'-UTRs of inflammatory mRNAs such as ceruloplasmin.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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