Thermo Fisher Scientific TNFRSF21 Monoclonal Antibody (6B8)
인간 TNFRSF21 단백질을 인식하는 Mouse IgG2b 단클론 항체. ELISA에 적합하며, 비결합형 액상 형태로 제공. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관. DR6 수용체 관련 세포사멸 연구에 활용 가능.
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Applications
- ELISA (ELISA): Tested dilution 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B8 |
| Immunogen | TNFRSF21 (AAH17730.1, 89 a.a. approximately 170 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SSCPVGTFTR HENGIEKCHD CSQPCPWPMI EKLPCAALTD RECTCPPGMF QSNATCAPHT VCPVGWGVRK KGTETEDVRC KQ
Target Information
DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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