Thermo Fisher Scientific TLR9 Polyclonal Antibody
Rabbit polyclonal antibody against human TLR9. Validated for WB and IHC(P). Recognizes synthetic peptide near the center of TLR9. Recommended positive control: Jurkat cell lysate. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–1.0 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to 15 residues near the center of human TLR9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087932 |
Product Specific Information
A suggested positive control for this product is Jurkat cell lysate.
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a key role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity.
This gene is preferentially expressed in immune cell–rich tissues such as spleen, lymph node, bone marrow, and peripheral blood leukocytes. Studies in mice and humans indicate that this receptor mediates cellular responses to unmethylated CpG dinucleotides in bacterial DNA, initiating an innate immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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