Thermo Fisher Scientific ATP5A1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Immunogen sequence:
SILEERILGA DTSVDLEETG RVLSIGDGIA RVHGLRNVQA EEMVEFSSGL KGMSLNLEPD NVGVVVFGND KLIKEGDIVK RTGAIVDVPV GEELLGRVVD

Target Information

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation.
ATP synthase consists of two linked multi-subunit complexes:

• F1: soluble catalytic core
• Fo: membrane-spanning proton channel

The catalytic portion contains 5 subunits (alpha, beta, gamma, delta, epsilon) assembled in a stoichiometry of 3 alpha, 3 beta, and one each of the other three.
The proton channel consists of three main subunits (a, b, c).
This gene encodes the alpha subunit of the catalytic core.
Alternatively spliced transcript variants encoding different isoforms have been identified.
Pseudogenes of this gene are located on chromosomes 9, 2, and 16.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.