Thermo Fisher Scientific TACSTD2/TROP2 Monoclonal Antibody (TACSTD2, 2151)
인간 TROP2 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB 및 IHC(P) 등 다양한 응용에 적합함. Recombinant TACSTD2(aa 31-274)로부터 유래된 면역원 사용. 단백질 A/G로 정제된 액상 형태이며, -20°C 이하에서 보관 권장.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TACSTD2, 2151 |
| Immunogen | Recombinant fragment of human TACSTD2 protein (around aa 31–274) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733.
This antigen belongs to a family of type I membrane proteins and functions as a cell surface receptor that transduces intracellular calcium signals.
Mutations in the TROP2 gene cause gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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