Thermo Fisher Scientific PRMT6 Monoclonal Antibody (PCRP-PRMT6-2C9)
Human PRMT6 단백질을 인식하는 mouse monoclonal antibody로, Flow Cytometry 및 Peptide Array에 사용 가능. Recombinant full-length human PRMT6를 면역원으로 제작. Protein A/G 정제, 200 µg/mL 농도의 액상 형태. 연구용으로만 사용 가능.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10⁶ cells
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-PRMT6-2C9 |
| Immunogen | Recombinant full-length human PRMT6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
This antibody is predicted to react with Rat.
Target Information
Protein arginine N-methyltransferase 6 (PRMT6) is a type I PRMT enzyme that forms omega-N monomethylarginine and asymmetric dimethylarginine derivatives on glycine- and arginine-rich substrates.
Acts as a transcriptional coactivator for steroid hormone receptors including ESR1, ESR2, PGR, and NR3C1.
Promotes fasting-induced transcriptional activation of the gluconeogenic program via methylation of the CRTC2 transcription coactivator.
May play a role in innate immunity against HIV-1 by methylating and impairing the function of viral proteins such as Tat, Rev, and Nucleocapsid protein p7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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