Thermo Fisher Scientific Human MYCT1 Synthetic Peptide
Human MYCT1 단백질의 카복시 말단 17개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. Polyclonal antibody PA5-34450의 블로킹 펩타이드로 사용 가능합니다. Human MYCT1 연구용으로 적합하며, 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP1492
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human MYCT1 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human MYCT1.
PEP-1492 can be used as a blocking peptide with polyclonal antibody PA5-34450.
Target Information
MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation.
MYCT1 binds to the promoters of several c-Myc-regulated genes, and phenotypes seen in MYCT1-overexpressing cells are thought to result from deregulation of these genes. RUNX1-ETO, a fusion protein of RUNX1 and ETO, is believed to affect proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
주의사항
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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