Thermo Fisher Scientific Oval Cell Marker Monoclonal Antibody (MIC1-1C3)
간의 증식성 덕트 세포를 특이적으로 인식하는 단클론 항체. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합. Rat IgG2a 형식의 비접합 항체로, Protein G 정제 및 PBS 버퍼에 0.09% sodium azide 포함. 4°C 보관, 동결 금지.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | - |
| Flow Cytometry (Flow) | 1:50–1:100 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MIC1-1C3 |
| Immunogen | Nonparenchymal cells from DDC-treated mice |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151850 |
Product Specific Information
This antibody is specific for hepatic proliferating duct cells.
Target Information
Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts. To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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