Thermo Fisher Scientific SOCS3 Monoclonal Antibody (OTI5D4), TrueMAB
SOCS3 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI5D4). Western blot, IHC, ICC/IF, Flow Cytometry에 사용 가능. Human 시료 반응성. Affinity chromatography로 정제된 액상 형태, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D4 |
| Immunogen | Full length human recombinant protein of human SOCS3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokine receptor signaling is negatively regulated by the SOCS (Suppressor of Cytokine Signaling) family, which includes eight members: SOCS1–7 and CIS. These proteins contain an N-terminal region, a central SH2 domain, and a C-terminal SOCS box. SOCS proteins function as part of a classical negative feedback loop controlling cytokine signal transduction through STAT-induced transcriptional mechanisms. Expression of SOCS genes is rapidly induced by cytokines, and each member inhibits signaling through distinct mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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