Thermo Fisher Scientific PRKCE Monoclonal Antibody (OTI1B4), Biotin, TrueMAB
인간 PRKCE 단백질을 표적으로 하는 Biotin 결합 단일클론 항체입니다. ELISA 및 Luminex 분석에 사용 가능하며, 친화 크로마토그래피로 정제되었습니다. PBS/BSA 용액에 보관되며, -20°C에서 냉동 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| ELISA (ELISA) | 1:250–1:1,000 | - |
| Luminex (LUM) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B4 |
| Immunogen | Full length human recombinant protein of human PRKCE produced in HEK293T cells |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
The PKC family of serine/threonine kinases, including PRKCE (PKC epsilon), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity.
PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent. Protein kinase C (PKC) can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are involved in diverse cellular signaling pathways. They also act as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and distinct cellular roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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