Thermo Fisher Scientific NAK Polyclonal Antibody, FITC
FITC로 표지된 Rabbit Polyclonal 항체로, TBK1/NAK 단백질을 인식합니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 사용 가능하며, 498/517 nm의 형광 특성을 가집니다. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
- 카탈로그번호
- TBK1-FITC
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within second intracellular loop of human TBK1 protein |
| Conjugate | FITC (Fluorescein isothiocyanate) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TBK1 (TANK-binding kinase 1, also known as NAK or T2K) is a serine/threonine kinase belonging to the IKK family. It plays a key role in NF-κB activation and IRF3 signaling, acting as an essential mediator of gene expression during immune and inflammatory responses. TBK1 phosphorylates IKKβ and contributes to activation of NF-κB by promoting degradation of IκB. It is activated by growth factors and PMA, functioning upstream of NIK and the IKK complex. TBK1 is also critical for protecting embryonic liver cells from apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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