Thermo Fisher Scientific LPIN3 Monoclonal Antibody (OTI3H3), TrueMAB
LPIN3 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 고순도 친화 크로마토그래피 정제 및 안정적 PBS/BSA/glycerol 버퍼로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H3 |
| Immunogen | Full length human recombinant protein of human LPIN3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Humans with lipodystrophy show loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice with mutations in the fatty liver dystrophy gene exhibit similar phenotypes. The mouse gene responsible for fatty liver dystrophy, Lpin1, encodes a nuclear protein called lipin. Lpin1 mRNA is highly expressed in adipose tissue and induced during preadipocyte differentiation, indicating its role in adipose tissue development and its relevance as a candidate gene for human lipodystrophy.
Database searches identified mouse and human sequences similar to Lpin1, including two related mouse genes and three human homologs.
- Human LPIN1: Chromosome 2p25
- Human LPIN2: Chromosome 18p11
- Human LPIN3: Chromosome 20q11-q12
- Mouse Lpin1, Lpin2, Lpin3: Chromosome 12, 17, and 2 respectively
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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