Thermo Fisher Scientific CENPH Monoclonal Antibody (OTI2E8), TrueMAB
Human CENPH 단백질에 특이적인 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있음. HEK293T에서 생산된 full length CENPH 항원을 이용해 제작. 액상 형태로 0.44 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E8 |
| Immunogen | Full length human recombinant protein of human CENPH produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.44 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation.
The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase.
It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase.
It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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