Thermo Fisher Scientific HNMT Monoclonal Antibody (432CT31.4.2)
Human HNMT 단백질을 인식하는 마우스 단클론 항체로, Western Blot 등 연구용 분석에 적합. 비결합형 액상 형태이며, PBS(pH 7.4)와 sodium azide를 포함. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 432CT31.4.2 |
| Immunogen | Purified His-tagged HNMT protein (fragment) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897487 |
Target Information
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase (HNMT) and oxidative deamination via diamine oxidase. HNMT is a cytosolic enzyme that uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, histamine neurotransmitter activity is regulated by N(tau)-methylation since diamine oxidase is absent in the central nervous system. A common genetic polymorphism affects the activity levels of this enzyme in red blood cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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