Thermo Fisher Scientific ATP2A1 Monoclonal Antibody (6F8)
ATP2A1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 ELISA에 적합. Human 시료에 반응하며 PBS buffer에 보관. SERCA1 ATPase 연구에 활용 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6F8 |
| Immunogen | ATP2A1 (NP_775293, 522–612 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
IDRCNYVRVG TTRVPLTGPV KEKIMAVIKE WGTGRDTLRC LALATRDTPP KREEMVLDDS ARFLEYETDL TFVGVVGMLD PPRKEVTGSI Q
Target Information
ATP-dependent calcium pumps help maintain low cytoplasmic free calcium concentrations. These pumps, located in intracellular organelles, belong to a family of enzymes known as sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases.
- SERCA1 gene: Exclusively expressed in type II (fast) skeletal muscle.
- SERCA2 gene: Tissue-dependent processing generates SERCA2a (type I skeletal, cardiac, smooth muscle) and SERCA2b (expressed in all cell types).
- SERCA3 gene: Found in non-muscle cells and less characterized.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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